Polynucleotides

£300.00

Polynucleotides are bioactive chains of DNA fragments (typically derived from salmon or trout) that work as regenerative skin boosters. Unlike dermal fillers or toxins, they don’t just “fill” or paralyze — they stimulate your skin to heal, hydrate and rejuvenate itself at a cellular level. Think of them as “deep vitamins” for your skin.

Treatment length

Treatments Option

Time

  • Polynucleotides

  • Small

    15 min

  • Large

    30 min

  • Polynucleotides +HA

  • Small

    15 min

  • Large

    30 min

  • Polynucleotides Eyes

  • Small

    15 min

  • Large

    30 min

Polynucleotides

£300.00

£300.00

Advanced regenerative skin treatment for natural radiance and long-term rejuvenation.

Polynucleotides are the next-generation biostimulatory injectables designed to revitalise your skin at the cellular level. Derived from purified DNA fragments (often sourced from salmon), they work by stimulating your skin’s natural healing mechanisms — improving elasticity, hydration and texture without adding volume or paralysing muscles.

How do Polynucleotides work?

  • Stimulate regeneration: They activate fibroblasts to produce collagen and elastin.
  • Deep hydration: Their unique structure attracts and retains water in skin tissues.
  • Anti-inflammatory: Help reduce redness and inflammation, ideal for sensitive or acne-prone skin.
  • Improve circulation: Promote angiogenesis, supporting healthier, brighter skin.

These injectable treatments target the underlying causes of dullness, sagging, and aging — not just the surface.

Who Is It For?

Polynucleotide injections are ideal for individuals who want to improve skin quality, not just appearance. This treatment is perfect if you:

  • Notice fine lines, crepiness or dullness in your skin
  • Want to hydrate and strengthen your skin from within
  • Are seeking a natural, regenerative alternative to fillers or Botox
  • Have sensitive or acne-prone skin that reacts to other treatments
  • Are dealing with dark circles, under-eye hollowness or redness
  • Have undergone laser, microneedling or peel treatments and want to speed up recovery
  • Want to prevent early signs of ageing or maintain youthful skin long-term

Polynucleotides are safe for all skin types and tones — and especially well-suited for those looking for subtle, yet powerful improvements in texture, tone, and luminosity.

What to Expect

  • Treatment time: 15-30 minutes
  • Anaesthetic: Optional topical numbing
  • Downtime: Minimal – some redness or swelling may occur
  • Recommended course: 2–4 sessions spaced 3–4 weeks apart
  • Results: Natural glow and firmness developing over several weeks, lasting up to 12 months

Additional Benefits

  • Stimulates collagen and elastin production
  • Improves skin hydration and elasticity
  • Smooths fine lines and wrinkles
  • Reduces redness and inflammation
  • Brightens dull, tired-looking skin
  • Aids recovery after laser, microneedling or peel treatments
  • Safe and effective for delicate areas including under-eyes and neck
  • Long-lasting results (up to 12 months)

Your Safety, Our Priority

All polynucleotide treatments at La Rose Clinic are performed by qualified aesthetic practitioners in our CQC-registered medical facility. We use only high-purity, clinically approved polynucleotide products and adhere to the latest evidence-based safety standards.

Close-up of Asian girl lower face, hand and shoulder, highlighting smooth skin and calm expression

Need help choosing ?

We offer comprehensive consultations to help you understand your skin, body, and wellness needs. Whether you have a specific concern or simply want expert advice, our clinicians are here to guide you without pressure.

Treatment Length

15-30 min

Results Seen

2-3 weeks

Duration of Results

12 months

Session Frequency

2–4 sessions spaced 3–4 weeks apart

Real Results

After

Before

La Rose Clinic Difference

What makes us different from other clinics

La Rose Clinic
Other Providers
Doctor-led treatments
Patient-Centric Environment
Advanced, Clinically proven treatments & products
CQC Registered

Polynucleotides FAQs

Yes — polynucleotides are biocompatible and widely used in regenerative medicine. Side effects are rare and typically mild.

Absolutely. Polynucleotides have anti-inflammatory properties, making them ideal for reactive or acne-prone skin.

Results begin to appear within 2–3 weeks and continue to improve over time as collagen and elastin production increases.

Polynucleotides do not add volume or affect muscle movement. They stimulate your skin’s own ability to regenerate and repair.